The Autodesk Vault Server 2013 uses .Net Framework 4.0 instead of 2.5. If you are updating an existing ADMS installation, you will probably be surprised that you get an ADMS system check error concerning the state of ASP.net.
Along with updates to the Microsoft SQL version which is probably required as detailed the Vault System Requirements sheet, you will need to switch versions by running the command line shown in the WikiHelp file below to re-register the new version of .Net Framework.
Ed. Note: Thanks to John Hackney for pointing this out.